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-Structure paper
Title | An epistatic ratchet constrains the direction of glucocorticoid receptor evolution |
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Journal, issue, pages | Nature, Vol. 461, Page 515-519, Year 2009 |
Publish date | Mar 16, 2009 (structure data deposition date) |
Authors | Bridgham, J.T. / Ortlund, E.A. / Thornton, J.W. |
External links | Nature / PubMed:19779450 |
Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | PDB-3gn8: |
Chemicals | ChemComp-DEX: ChemComp-HOH: |
Source |
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Keywords | HORMONE/HORMONE ACTIVATOR / nuclear receptor / GR2 / evolution / glucocorticoid receptor / dexamethasone / cortisol / Activator / Nucleus / Phosphoprotein / Polymorphism / Transcription / Transcription regulation / HORMONE-HORMONE ACTIVATOR COMPLEX |