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TitleHigh resolution NMR-based model for the structure of a scFv-IL-1beta complex: potential for NMR as a key tool in therapeutic antibody design and development.
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 31928-31935, Year 2009
Publish dateMar 23, 2009 (structure data deposition date)
AuthorsWilkinson, I.C. / Hall, C.J. / Veverka, V. / Shi, J.Y. / Muskett, F.W. / Stephens, P.E. / Taylor, R.J. / Henry, A.J. / Carr, M.D.
External linksJ. Biol. Chem. / PubMed:19776018
MethodsNMR (solution)
Structure data

PDB-2kh2:
Solution structure of a scFv-IL-1B complex
Method: SOLUTION NMR

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsCytokine/IMMUNE SYSTEM / scFv / single chain Fv / IL-1B / antibody / Cytokine / Inflammatory response / Mitogen / Pyrogen / Secreted / Cytokine-IMMUNE SYSTEM COMPLEX

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