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TitleMolecular basis of reduced pyridoxine 5'-phosphate oxidase catalytic activity in neonatal epileptic encephalopathy disorder
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 30949-30956, Year 2009
Publish dateJun 22, 2009 (structure data deposition date)
AuthorsMusayev, F.N. / Di Salvo, M.L. / Saavedra, M.A. / Contestabile, R. / Ghatge, M.S. / Haynes, A. / Schirch, V. / Safo, M.K.
External linksJ. Biol. Chem. / PubMed:19759001
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-3hy8:
Crystal Structure of Human Pyridoxine 5'-Phosphate Oxidase R229W Mutant
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / FMN binding protein / oxidase / Disease mutation / Epilepsy / Flavoprotein / FMN / Phosphoprotein / Pyridoxal phosphate / Pyridoxine biosynthesis

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