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TitleDiscovery of Specific Flavodoxin Inhibitors as Potential Therapeutic Agents Against Helicobacter Pylori Infection.
Journal, issue, pagesAcs Chem. Biol., Vol. 4, Page 928-, Year 2009
Publish dateDec 12, 2008 (structure data deposition date)
AuthorsCremades, N. / Velazquez-Campoy, A. / Martinez-Julvez, M. / Neira, J.L. / Perez-Dorado, I. / Hermoso, J. / Jimenez, P. / Lanas, A. / Hoffman, P.S. / Sancho, J.
External linksAcs Chem. Biol. / PubMed:19725577
MethodsX-ray diffraction
Resolution2.62 Å
Structure data

PDB-2w5u:
Flavodoxin from Helicobacter pylori in complex with the C3 inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.62 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-IC3:
[2-(5-amino-4-cyano-1H-pyrazol-1-yl)-5-(trifluoromethyl)phenyl](hydroxy)oxoammonium

ChemComp-HOH:
WATER

Source
  • helicobacter pylori (bacteria)
KeywordsELECTRON TRANSPORT / DRUG DISCOVERY / PROTEIN HINHIBITOR / FMN / TRANSPORT / FLAVODOXIN / FLAVOPROTEIN

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