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Structure paper

TitleStructural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 106, Page 15616-15621, Year 2009
Publish dateApr 28, 2009 (structure data deposition date)
AuthorsUmitsu, M. / Nishimasu, H. / Noma, A. / Suzuki, T. / Ishitani, R. / Nureki, O.
External linksProc. Natl. Acad. Sci. USA / PubMed:19717466
MethodsX-ray diffraction
Resolution2.005 - 2.5 Å
Structure data

PDB-3a25:
Crystal structure of P. horikoshii TYW2 in complex with AdoMet
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3a26:
Crystal structure of P. horikoshii TYW2 in complex with MeSAdo
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3a27:
Crystal structure of M. jannaschii TYW2 in complex with AdoMet
Method: X-RAY DIFFRACTION / Resolution: 2.005 Å

Chemicals

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-HOH:
WATER

ChemComp-MTA:
5'-DEOXY-5'-METHYLTHIOADENOSINE

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

Source
  • pyrococcus horikoshii (archaea)
  • methanocaldococcus jannaschii (archaea)
KeywordsTRANSFERASE / Wybutosine modification

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