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Structure paper

TitleA Genetically Encoded Photoactivatable Rac Controls the Motility of Living Cells.
Journal, issue, pagesNature, Vol. 461, Page 104-, Year 2009
Publish dateJun 16, 2009 (structure data deposition date)
AuthorsWu, Y.I. / Frey, D. / Lungu, O.I. / Jaehrig, A. / Schlichting, I. / Kuhlman, B. / Hahn, K.M.
External linksNature / PubMed:19693014
MethodsX-ray diffraction
Resolution1.6 - 2.2 Å
Structure data

PDB-2wkp:
Structure of a photoactivatable Rac1 containing Lov2 Wildtype
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2wkq:
Structure of a photoactivatable Rac1 containing the Lov2 C450A Mutant
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-2wkr:
Structure of a photoactivatable Rac1 containing the Lov2 C450M Mutant
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-MG:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • avena sativa (oats)
  • homo sapiens (human)
KeywordsTRANSFERASE / CELL ADHESION / GTPASE / SMALL G-PROTEIN / RHO FAMILY / RAS SUPERFAMILY LOV2 / ATP-BINDING / LIGHT-INDUCED SIGNAL TRANSDUCTION / LOV2 / PHOTOTROPIN1 / NUCLEOTIDE-BINDING PROTEIN ENGINEERING / PROTEIN DESIGN / CHIMERA / NUCLEOTIDE-BINDING / PROTEIN ENGINEERING / LIGHT- INDUCED SIGNAL TRANSDUCTION / ALTERNATIVE SPLICING / CELL MEMBRANE / ADP-RIBOSYLATION / LIPOPROTEIN / GTP-BINDING / PRENYLATION

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