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TitleConformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7.
Journal, issue, pagesApoptosis, Vol. 14, Page 1135-1144, Year 2009
Publish dateJul 15, 2009 (structure data deposition date)
AuthorsAgniswamy, J. / Fang, B. / Weber, I.T.
External linksApoptosis / PubMed:19655253
MethodsX-ray diffraction
Resolution2.5 - 2.75 Å
Structure data

PDB-3ibc:
Crystal Structure of Caspase-7 incomplex with Acetyl-YVAD-CHO
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-3ibf:
Crystal structure of unliganded caspase-7
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
Keywordshydrolase / apoptosis / protein-peptide complex / Alternative splicing / Cytoplasm / Polymorphism / Protease / Thiol protease / Zymogen / protein structure

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