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TitleStructure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV).
Journal, issue, pagesJ. Mol. Biol., Vol. 392, Page 977-993, Year 2009
Publish dateNov 17, 2008 (structure data deposition date)
AuthorsTian, X. / Lu, G. / Gao, F. / Peng, H. / Feng, Y. / Ma, G. / Bartlam, M. / Tian, K. / Yan, J. / Hilgenfeld, R. / Gao, G.F.
External linksJ. Mol. Biol. / PubMed:19646449
MethodsX-ray diffraction
Resolution1.9 - 2.01 Å
Structure data

PDB-3fan:
Crystal structure of chymotrypsin-like protease/proteinase (3CLSP/Nsp4) of porcine reproductive and respiratory syndrome virus (PRRSV)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3fao:
Crystal structure of S118A mutant 3CLSP of PRRSV
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • porcine respiratory and reproductive syndrome virus
KeywordsHYDROLASE / chymotrypsin-like / N-terminal beta-barrels / C-terminal alpha-beta extra domain / canonical catalytic triad / S118A mutant

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