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TitleCrystal structure of a phospholipase A(2) homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity.
Journal, issue, pagesBiochim. Biophys. Acta, Vol. 1794, Page 1583-1590, Year 2009
Publish dateJan 16, 2007 (structure data deposition date)
AuthorsMarchi-Salvador, D.P. / Fernandes, C.A. / Silveira, L.B. / Soares, A.M. / Fontes, M.R.
External linksBiochim. Biophys. Acta / PubMed:19616648
MethodsX-ray diffraction
Resolution2.34 Å
Structure data

PDB-2ok9:
PrTX-I-BPB
Method: X-RAY DIFFRACTION / Resolution: 2.34 Å

Chemicals

ChemComp-PBP:
p-Bromophenacyl bromide

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-HOH:
WATER

Source
  • bothrops pirajai (snake)
KeywordsTOXIN / PrTX-I-BPB complex / Lys49-PLA2 / Bothrops pirajai / Piratoxin I

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