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TitleStructure of the lamin A/C R482W mutant responsible for dominant familial partial lipodystrophy (FPLD).
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 65, Page 665-670, Year 2009
Publish dateFeb 25, 2009 (structure data deposition date)
AuthorsMagracheva, E. / Kozlov, S. / Stewart, C.L. / Wlodawer, A. / Zdanov, A.
External linksActa Crystallogr. ,Sect. F / PubMed:19574635
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-3gef:
Crystal structure of the R482W mutant of lamin A/C
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / immunoglobulin fold / lamin / Cardiomyopathy / Charcot-Marie-Tooth disease / Disease mutation / Intermediate filament / Limb-girdle muscular dystrophy / Lipoprotein / Nucleus / Phosphoprotein / Prenylation

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