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-Structure paper
Title | Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. |
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Journal, issue, pages | Cell(Cambridge,Mass. ), Vol. 137, Page 1293-1307, Year 2009 |
Publish date | Mar 27, 2009 (structure data deposition date) |
Authors | Jura, N. / Endres, N.F. / Engel, K. / Deindl, S. / Das, R. / Lamers, M.H. / Wemmer, D.E. / Zhang, X. / Kuriyan, J. |
External links | Cell(Cambridge,Mass. ) / PubMed:19563760 |
Methods | X-ray diffraction |
Resolution | 2.955 Å |
Structure data | PDB-3gt8: |
Chemicals | ChemComp-ANP: ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / inactive kinase / dimer / Alternative splicing / Anti-oncogene / ATP-binding / Cell cycle / Cell membrane / Disease mutation / Disulfide bond / Glycoprotein / Isopeptide bond / Kinase / Membrane / Nucleotide-binding / Phosphoprotein / Polymorphism / Receptor / Secreted / Transmembrane / Tyrosine-protein kinase / Ubl conjugation |