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Structure paper

TitleStructural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Journal, issue, pagesMol. Cell, Vol. 34, Page 710-721, Year 2009
Publish dateJun 3, 2009 (structure data deposition date)
AuthorsSydow, J.F. / Brueckner, F. / Cheung, A.C.M. / Damsma, G.E. / Dengl, S. / Lehmann, E. / Vassylyev, D. / Cramer, P.
External linksMol. Cell / PubMed:19560423
MethodsX-ray diffraction
Resolution3.2 - 3.65 Å
Structure data

PDB-3hou:
Complete RNA polymerase II elongation complex I with a T-U mismatch
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-3hov:
Complete RNA polymerase II elongation complex II
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-3how:
Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

PDB-3hox:
Complete RNA polymerase II elongation complex V
Method: X-RAY DIFFRACTION / Resolution: 3.65 Å

PDB-3hoy:
Complete RNA polymerase II elongation complex VI
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

PDB-3hoz:
Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3'-guanine
Method: X-RAY DIFFRACTION / Resolution: 3.65 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsTRANSCRIPTION / TRANSFERASE/DNA/RNA HYBRID / RNA POLYMERASE II / METAL-BINDING / TRANSCRIPTION BUBBLE / ELONGATION COMPLEX / DNA-RNA MISMATCH / DNA-binding / DNA-directed RNA polymerase / Isopeptide bond / Magnesium / Nucleotidyltransferase / Nucleus / Phosphoprotein / Transferase / Ubl conjugation / Zinc / Zinc-finger / Polymorphism / Cytoplasm / DNA damage / DNA repair / mRNA processing / TRANSFERASE-DNA-RNA HYBRID COMPLEX / TRANSFERASE/DNA/RNA / TRANSFERASE-DNA-RNA COMPLEX / RNA fraying / RNA-FRAYING / METAL BINDING

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