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TitleL2' loop is critical for caspase-7 active site formation.
Journal, issue, pagesProtein Sci., Vol. 18, Page 1459-1468, Year 2009
Publish dateApr 13, 2009 (structure data deposition date)
AuthorsWitkowski, W.A. / Hardy, J.A.
External linksProtein Sci. / PubMed:19530232
MethodsX-ray diffraction
Resolution2.61 Å
Structure data

PDB-3h1p:
Mature Caspase-7 I213A with DEVD-CHO inhibitor bound to active site
Method: X-RAY DIFFRACTION / Resolution: 2.61 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/INHIBITOR / protease / compensatory mechanism / apoptosis / cell death / cysteine protease / Thiol protease / Zymogen / HYDROLASE-INHIBITOR complex

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