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TitleFlipping of alkylated DNA damage bridges base and nucleotide excision repair.
Journal, issue, pagesNature, Vol. 459, Page 808-813, Year 2009
Publish dateMar 30, 2009 (structure data deposition date)
AuthorsTubbs, J.L. / Latypov, V. / Kanugula, S. / Butt, A. / Melikishvili, M. / Kraehenbuehl, R. / Fleck, O. / Marriott, A. / Watson, A.J. / Verbeek, B. ...Tubbs, J.L. / Latypov, V. / Kanugula, S. / Butt, A. / Melikishvili, M. / Kraehenbuehl, R. / Fleck, O. / Marriott, A. / Watson, A.J. / Verbeek, B. / McGown, G. / Thorncroft, M. / Santibanez-Koref, M.F. / Millington, C. / Arvai, A.S. / Kroeger, M.D. / Peterson, L.A. / Williams, D.M. / Fried, M.G. / Margison, G.P. / Pegg, A.E. / Tainer, J.A.
External linksNature / PubMed:19516334
MethodsX-ray diffraction
Resolution2 - 2.8 Å
Structure data

PDB-3gva:
Crystal Structure Analysis of S. Pombe ATL
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3gx4:
Crystal Structure Analysis of S. Pombe ATL in complex with DNA
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-3gyh:
Crystal Structure Analysis of S. Pombe ATL in complex with damaged DNA containing POB
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NCO:
COBALT HEXAMMINE(III)

ChemComp-PBO:
1-PYRIDIN-3-YLBUTAN-1-ONE

Source
  • schizosaccharomyces pombe (fission yeast)
KeywordsDNA BINDING PROTEIN / Alkylated DNA damage repair / DNA damage / DNA repair / DNA-binding / DNA BINDING PROTEIN/DNA / Alkylated DNA damage repair Methylguanine / DNA BINDING PROTEIN-DNA COMPLEX

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