+Search query
-Structure paper
Title | Dipeptidyl nitrile inhibitors of Cathepsin L. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 19, Page 4280-4283, Year 2009 |
Publish date | May 15, 2009 (structure data deposition date) |
Authors | Asaad, N. / Bethel, P.A. / Coulson, M.D. / Dawson, J.E. / Ford, S.J. / Gerhardt, S. / Grist, M. / Hamlin, G.A. / James, M.J. / Jones, E.V. ...Asaad, N. / Bethel, P.A. / Coulson, M.D. / Dawson, J.E. / Ford, S.J. / Gerhardt, S. / Grist, M. / Hamlin, G.A. / James, M.J. / Jones, E.V. / Karoutchi, G.I. / Kenny, P.W. / Morley, A.D. / Oldham, K. / Rankine, N. / Ryan, D. / Wells, S.L. / Wood, L. / Augustin, M. / Krapp, S. / Simader, H. / Steinbacher, S. |
External links | Bioorg. Med. Chem. Lett. / PubMed:19515558 |
Methods | X-ray diffraction |
Resolution | 1.27 Å |
Structure data | PDB-3hha: |
Chemicals | ChemComp-NOW: ChemComp-PG4: ChemComp-ACT: ChemComp-PGE: ChemComp-GOL: ChemComp-HOH: |
Source |
|
Keywords | HYDROLASE / PROTEROS BIOSTRUCTURES GMBH / Cathepsin L / Inhibitors / Disulfide bond / Glycoprotein / Lysosome / Protease / Thiol protease / Zymogen |