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-Structure paper
Title | ATP and MO25alpha regulate the conformational state of the STRADalpha pseudokinase and activation of the LKB1 tumour suppressor |
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Journal, issue, pages | Plos Biol., Vol. 7, Page e1000126-e1000126, Year 2009 |
Publish date | Mar 17, 2009 (structure data deposition date) |
Authors | Zeqiraj, E. / Filippi, B.M. / Goldie, S. / Navratilova, I. / Boudeau, J. / Deak, M. / Alessi, D.R. / van Aalten, D.M. |
External links | Plos Biol. / PubMed:19513107 |
Methods | X-ray diffraction |
Resolution | 2.35 Å |
Structure data | PDB-3gni: |
Chemicals | ChemComp-CIT: ChemComp-ATP: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN/SIGNALING PROTEIN / kinase fold / pseudokinase / alpha helical repeat protein / adaptor protein / ATP-binding / Cell cycle / Kinase / Nucleotide-binding / Nucleus / Phosphoprotein / Transferase / METAL BINDING PROTEIN-TRANSFERASE COMPLEX / SIGNALING PROTEIN-SIGNALING PROTEIN COMPLEX |