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Structure paper

TitleStructure of complement fragment C3b-factor H and implications for host protection by complement regulators.
Journal, issue, pagesNat. Immunol., Vol. 10, Page 728-733, Year 2009
Publish dateMay 12, 2009 (structure data deposition date)
AuthorsWu, J. / Wu, Y.Q. / Ricklin, D. / Janssen, B.J. / Lambris, J.D. / Gros, P.
External linksNat. Immunol. / PubMed:19503104
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-2wii:
Complement C3b in complex with factor H domains 1-4
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / SUSHI / SECRETED / POLYMORPHISM / GLYCOPROTEIN / COMPLEMENT SYSTEM / COMPLEMENT PATHWAY / IMMUNE RESPONSE / INNATE IMMUNITY / DISEASE MUTATION / INFLAMMATORY RESPONSE / COMPLEMENT ALTERNATE PATHWAY / CLEAVAGE ON PAIR OF BASIC RESIDUES / AGE-RELATED MACULAR DEGENERATION / REGULATOR OF COMPLEMENT ACTIVATION / ALTERNATIVE PATHWAY / ALTERNATIVE SPLICING / PHOSPHOPROTEIN / DISULFIDE BOND / THIOESTER BOND

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