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-Structure paper
Title | Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo. |
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Journal, issue, pages | Cancer Res., Vol. 69, Page 4791-4799, Year 2009 |
Publish date | Feb 9, 2009 (structure data deposition date) |
Authors | Fuchita, M. / Ardiani, A. / Zhao, L. / Serve, K. / Stoddard, B.L. / Black, M.E. |
External links | Cancer Res. / PubMed:19487291 |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | PDB-3g77: |
Chemicals | ChemComp-FE: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / cytosine deaminase / protein engineering / Cytosine metabolism / Iron / Metal-binding |