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Structure paper

TitleStructural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Journal, issue, pagesScience, Vol. 324, Page 1203-1206, Year 2009
Publish dateMar 27, 2009 (structure data deposition date)
AuthorsWang, D. / Bushnell, D.A. / Huang, X. / Westover, K.D. / Levitt, M. / Kornberg, R.D.
External linksScience / PubMed:19478184
MethodsX-ray diffraction
Resolution3.38 - 4 Å
Structure data

PDB-3gtg:
Backtracked RNA polymerase II complex with 12mer RNA
Method: X-RAY DIFFRACTION / Resolution: 3.78 Å

PDB-3gtj:
Backtracked RNA polymerase II complex with 13mer RNA
Method: X-RAY DIFFRACTION / Resolution: 3.42 Å

PDB-3gtk:
Backtracked RNA polymerase II complex with 18mer RNA
Method: X-RAY DIFFRACTION / Resolution: 3.8 Å

PDB-3gtl:
Backtracked RNA polymerase II complex with 13mer with G<>U mismatch
Method: X-RAY DIFFRACTION / Resolution: 3.38 Å

PDB-3gtm:
Co-complex of Backtracked RNA polymerase II with TFIIS
Method: X-RAY DIFFRACTION / Resolution: 3.8 Å

PDB-3gto:
Backtracked RNA polymerase II complex with 15mer RNA
Method: X-RAY DIFFRACTION / Resolution: 4.0 Å

PDB-3gtp:
Backtracked RNA polymerase II complex with 24mer RNA
Method: X-RAY DIFFRACTION / Resolution: 3.9 Å

PDB-3gtq:
Backtracked RNA polymerase II complex induced by damage
Method: X-RAY DIFFRACTION / Resolution: 3.8 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER / Water

Source
  • saccharomyces cerevisiae (brewer's yeast)
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
  • synthetic construct (others)
KeywordsTRANSCRIPTION / TRANSFERASE/DNA/RNA HYBRID / TRANSFERASE/DNA-RNA HYBRID / DNA-directed RNA polymerase / DNA binding / Isopeptide bond / Magnesium / Metal binding / Nucleotidyltransferase / Nucleus / Phosphoprotein / Transferase / Ubl conjugation / Zinc / Zinc-finger / Polymorphism / Cytoplasm / DNA damage / DNA repair / TRANSFERASE-DNA-RNA HYBRID COMPLEX / DNA-RNA HYBRID / Backtrack / Transcription regulation

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