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TitleStructural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone).
Journal, issue, pagesChem. Biol., Vol. 16, Page 557-566, Year 2009
Publish dateMar 13, 2009 (structure data deposition date)
AuthorsZheng, S. / Chen, Y. / Donahue, C.P. / Wolfe, M.S. / Varani, G.
External linksChem. Biol. / PubMed:19477420
MethodsNMR (solution)
Structure data

PDB-2kgp:
Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by Novantrone (Mitoxantrone)
Method: SOLUTION NMR

Chemicals

ChemComp-MIX:
1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE / antineoplastic*YM

KeywordsRNA / tau pre-mRNA / splicing regulatory element / Mitoxantrone / Novantrone / RNA-small molecule / Tauopathies

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