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Structure paper

TitleImpact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Journal, issue, pagesStructure, Vol. 17, Page 725-736, Year 2009
Publish dateMar 5, 2009 (structure data deposition date)
AuthorsRechkoblit, O. / Malinina, L. / Cheng, Y. / Geacintov, N.E. / Broyde, S. / Patel, D.J.
External linksStructure / PubMed:19446528
MethodsX-ray diffraction
Resolution2.4 - 2.9 Å
Structure data

PDB-3gii:
Dpo4 extension ternary complex with disordered A opposite an oxoG in anti conformation
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3gij:
Dpo4 extension ternary complex with oxoG(syn)-A(anti) and oxoG(anti)-A(syn) pairs
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3gik:
Dpo4 extension ternary complex with the oxoG(anti)-C(anti) pair
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3gil:
Dpo4 extension ternary complex with oxoG(anti)-T(anti) pair
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

PDB-3gim:
Dpo4 extension ternary complex with oxoG(anti)-G(syn) pair
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-DGT:
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-CA:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • sulfolobus solfataricus p2 (archaea)
KeywordsTRANSFERASE/DNA / DNA POLYMERASE / 8-OXOGUANINE / Y-FAMILY / LESION BYPASS / DNA damage / DNA repair / DNA replication / DNA-binding / DNA-directed DNA polymerase / Magnesium / Metal-binding / Mutator protein / Nucleotidyltransferase / Transferase / TRANSFERASE-DNA COMPLEX

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