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Structure paper

TitleStructures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.
Journal, issue, pagesJ. Mol. Biol., Vol. 389, Page 722-733, Year 2009
Publish dateMay 28, 2008 (structure data deposition date)
AuthorsZhang, Z. / Caradoc-Davies, T.T. / Dickson, J.M. / Baker, E.N. / Squire, C.J.
External linksJ. Mol. Biol. / PubMed:19394344
MethodsX-ray diffraction
Resolution1.3 - 2.2 Å
Structure data

PDB-3da8:
Crystal structure of PurN from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-3dcj:
Crystal structure of glycinamide formyltransferase (PurN) from Mycobacterium tuberculosis in complex with 5-methyl-5,6,7,8-tetrahydrofolic acid derivative
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-IOD:
IODIDE ION

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-HOH:
WATER

ChemComp-THH:
N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID

ChemComp-CL:
Unknown entry

ChemComp-NO3:
NITRATE ION

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsTRANSFERASE / glycinamide ribonucleotide transformylase / PurN / GLYCINAMIDE FORMYLTRANSFERASE

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