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Structure paper

TitleDNA Synthesis across an Abasic Lesion by Human DNA Polymerase iota
Journal, issue, pagesStructure, Vol. 17, Page 530-537, Year 2009
Publish dateFeb 9, 2009 (structure data deposition date)
AuthorsNair, D.T. / Johnson, R.E. / Prakash, L. / Prakash, S. / Aggarwal, A.K.
External linksStructure / PubMed:19368886
MethodsX-ray diffraction
Resolution2.08 - 2.2 Å
Structure data

PDB-3g6v:
DNA synthesis across an abasic lesion by human DNA polymerase-iota
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3g6x:
Ternary complex of DNA Polymerase iota:DNA:dGTP with an abasic site at the templating position
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

PDB-3g6y:
Ternary complex of DNA Polymerase iota:DNA:dTTP with an abasic site at the templating position
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-DGT:
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-TTP:
THYMIDINE-5'-TRIPHOSPHATE

Source
  • homo sapiens (human)
KeywordsREPLICATION/DNA / DNA Polymerase / Y-family / Lesion Bypass / abasic site / ternary complex / DNA damage / DNA repair / DNA replication / DNA synthesis / DNA-binding / DNA-directed DNA polymerase / Magnesium / Metal-binding / Mutator protein / Nucleotidyltransferase / Nucleus / Schiff base / Transferase / REPLICATION-DNA COMPLEX

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