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-Structure paper
Title | Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 19, Page 2718-2721, Year 2009 |
Publish date | Mar 19, 2009 (structure data deposition date) |
![]() | Mitsuya, M. / Kamata, K. / Bamba, M. / Watanabe, H. / Sasaki, Y. / Sasaki, K. / Ohyama, S. / Hosaka, H. / Nagata, Y. / Eiki, J. / Nishimura, T. |
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Methods | X-ray diffraction |
Resolution | 2.2 - 2.52 Å |
Structure data | ![]() PDB-3a0i: ![]() PDB-3goi: |
Chemicals | ![]() ChemComp-GLC: ![]() ChemComp-AJI: ![]() ChemComp-NA: ![]() ChemComp-HOH: ![]() ChemComp-LOI: |
Source |
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![]() | TRANSFERASE / Glucokinase / Diabetes / Activator / Alternative splicing / ATP-binding / Diabetes mellitus / Disease mutation / Glycolysis / Kinase / Nucleotide-binding / Polymorphism / allosteric activator |