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TitleStructural basis for antibody discrimination between two hormones that recognize the parathyroid hormone receptor
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 15557-15563, Year 2009
Publish dateDec 3, 2008 (structure data deposition date)
AuthorsMcKinstry, W.J. / Polekhina, G. / Diefenbach-Jagger, H. / Ho, P.W.M. / Sato, K. / Onuma, E. / Gillespie, M.T. / Martin, T.J. / Parker, M.W.
External linksJ. Biol. Chem. / PubMed:19346515
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-3ffd:
Structure of parathyroid hormone-related protein complexed to a neutralizing monoclonal antibody
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM/HORMONE / pthrp complexed to fab / Cleavage on pair of basic residues / Hormone / Nucleus / Secreted / IMMUNE SYSTEM-HORMONE COMPLEX

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