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Structure paper

TitleInvestigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Journal, issue, pagesBiochemistry, Vol. 30, Page 11092-11103, Year 1991
Publish dateJun 10, 1992 (structure data deposition date)
AuthorsWarren, M.S. / Brown, K.A. / Farnum, M.F. / Howell, E.E. / Kraut, J.
External linksBiochemistry / PubMed:1932031
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-2drc:
INVESTIGATION OF THE FUNCTIONAL ROLE OF TRYPTOPHAN-22 IN ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE BY SITE-DIRECTED MUTAGENESIS
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3drc:
INVESTIGATION OF THE FUNCTIONAL ROLE OF TRYPTOPHAN-22 IN ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE BY SITE-DIRECTED MUTAGENESIS
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-MTX:
METHOTREXATE / chemotherapy*YM

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsOXIDOREDUCTASE

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