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TitleT Cell-Mediated Autoimmune Disease due to Low-Affinity Crossreactivity to Common Microbial Peptides.
Journal, issue, pagesImmunity, Vol. 30, Page 348-, Year 2009
Publish dateMar 2, 2009 (structure data deposition date)
AuthorsHarkiolaki, M. / Holmes, S.L. / Svendsen, P. / Gregersen, J.W. / Jensen, L.T. / Mcmahon, R. / Friese, M.A. / Van Boxel, G. / Etzensperger, R. / Tzartos, J.S. ...Harkiolaki, M. / Holmes, S.L. / Svendsen, P. / Gregersen, J.W. / Jensen, L.T. / Mcmahon, R. / Friese, M.A. / Van Boxel, G. / Etzensperger, R. / Tzartos, J.S. / Kranc, K. / Sainsbury, S. / Harlos, K. / Mellins, E.D. / Palace, J. / Esiri, M.M. / Van Der Merwe, P.A. / Jones, E.Y. / Fugger, L.
External linksImmunity / PubMed:19303388
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-2wbj:
TCR complex
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / TRANSMEMBRANE / IMMUNE RESPONSE / T CELL RECEPTOR / MHC II / MEMBRANE / RECEPTOR / MOLECULAR MIMICRY / MULTIPLE SCLEROSIS / AUTOIMMUNITY / GLYCOPROTEIN / MHC CLASS II

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