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| Title | Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 52, Page 2618-2622, Year 2009 |
| Publish date | Feb 19, 2009 (structure data deposition date) |
 Authors | Lin, C.-H. / Peng, Y.-H. / Coumar, M.S. / Chittimalla, S.K. / Liao, C.-C. / Lyn, P.-C. / Huang, C.-C. / Lien, T.-W. / Lin, W.-H. / Hsu, J.T.-A. ...Lin, C.-H. / Peng, Y.-H. / Coumar, M.S. / Chittimalla, S.K. / Liao, C.-C. / Lyn, P.-C. / Huang, C.-C. / Lien, T.-W. / Lin, W.-H. / Hsu, J.T.-A. / Cheng, J.-H. / Chen, X. / Wu, J.-S. / Chao, Y.-S. / Lee, H.-J. / Juo, C.-G. / Wu, S.-Y. / Hsieh, H.-P. |
 External links | J. Med. Chem. / PubMed:19301897 |
| Methods | X-ray diffraction |
| Resolution | 2.3 Å |
| Structure data |  PDB-3gbk: |
| Chemicals |  ChemComp-2PQ:  ChemComp-HOH: |
| Source |
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 Keywords | ligand binding protein / PPAR aganists / x-ray co-crystal analysis / Structure-based drug design / selective / Type II Diabetes / Activator / Alternative splicing / Diabetes mellitus / Disease mutation / DNA-binding / Metal-binding / Nucleus / Obesity / Phosphoprotein / Polymorphism / Receptor / Transcription / Transcription regulation / Zinc / Zinc-finger |
homo sapiens (human)