+Search query
-Structure paper
Title | (3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 19, Page 1991-1995, Year 2009 |
Publish date | Nov 13, 2008 (structure data deposition date) |
![]() | Ammirati, M.J. / Andrews, K.M. / Boyer, D.D. / Brodeur, A.M. / Danley, D.E. / Doran, S.D. / Hulin, B. / Liu, S. / McPherson, R.K. / Orena, S.J. ...Ammirati, M.J. / Andrews, K.M. / Boyer, D.D. / Brodeur, A.M. / Danley, D.E. / Doran, S.D. / Hulin, B. / Liu, S. / McPherson, R.K. / Orena, S.J. / Parker, J.C. / Polivkova, J. / Qiu, X. / Soglia, C.B. / Treadway, J.L. / VanVolkenburg, M.A. / Wilder, D.C. / Piotrowski, D.W. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.43 Å |
Structure data | ![]() PDB-3f8s: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-PF2: |
Source |
|
![]() | HYDROLASE / Dipeptidyl peptidase 4 / complex / Aminopeptidase / Glycoprotein / Membrane / Protease / Secreted / Serine protease / Signal-anchor / Transmembrane |