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Structure paper

TitleThe structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
Journal, issue, pagesNature, Vol. 458, Page 1191-1195, Year 2009
Publish dateJan 21, 2009 (structure data deposition date)
AuthorsPark, B.S. / Song, D.H. / Kim, H.M. / Choi, B.-S. / Lee, H. / Lee, J.-O.
External linksNature / PubMed:19252480
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-3fxi:
Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-FTT:
3-HYDROXY-TETRADECANOIC ACID

ChemComp-DAO:
LAURIC ACID

ChemComp-MYR:
MYRISTIC ACID

ChemComp-PO4:
PHOSPHATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Leucine Rich Repeat / Glycoprotein / Immune response / Inflammatory response / Innate immunity / Membrane / Receptor / Transmembrane / Secreted

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