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Structure paper

TitleStructural characterization of a human Fc fragment engineered for extended serum half-life.
Journal, issue, pagesMol. Immunol., Vol. 46, Page 1750-1755, Year 2009
Publish dateDec 15, 2008 (structure data deposition date)
AuthorsOganesyan, V. / Damschroder, M.M. / Woods, R.M. / Cook, K.E. / Wu, H. / Dall'acqua, W.F.
External linksMol. Immunol. / PubMed:19250681
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-3fjt:
Crystal structure of a human Fc fragment engineered for extended serum half-life
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Fc / IgG1 / FcRn binding / CH3-CH3 association / Glycoprotein / Immunoglobulin C region / Immunoglobulin domain / Secreted

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