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Structure paper

TitleCrystal Structure of Human Cdk4 in Complex with a D-Type Cyclin.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 106, Page 4166-, Year 2009
Publish dateJan 21, 2009 (structure data deposition date)
AuthorsDay, P.J. / Cleasby, A. / Tickle, I.J. / O'Reilly, M. / Coyle, J.E. / Holding, F.P. / Mcmenamin, R.L. / Yon, J. / Chopra, R. / Lengauer, C. / Jhoti, H.
External linksProc. Natl. Acad. Sci. USA / PubMed:19237565
MethodsX-ray diffraction
Resolution2.3 - 2.85 Å
Structure data

PDB-2w96:
Crystal Structure of CDK4 in complex with a D-type cyclin
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2w99:
Crystal Structure of CDK4 in complex with a D-type cyclin
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-2w9f:
Crystal Structure of CDK4 in complex with a D-type cyclin
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-2w9z:
Crystal Structure of CDK4 in complex with a D-type cyclin
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / SERINE/THREONINE-PROTEIN KINASE / CHROMOSOMAL REARRANGEMENT / ATP-BINDING / TRANSFERASE / POLYMORPHISM / CELL DIVISION / PROTO-ONCOGENE / PHOSPHOPROTEIN / DISEASE MUTATION / NUCLEOTIDE-BINDING / CYCLIN DEPENDENT KINASE / KINASE / CYCLIN / ONCOLOGY / DRUG DESGN / TRANSFERASE ONCOLOGY / DRUG DESIGN

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