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Structure paper

TitleCrystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity.
Journal, issue, pagesEmbo J., Vol. 28, Page 937-947, Year 2009
Publish dateOct 13, 2008 (structure data deposition date)
AuthorsKotzsch, A. / Nickel, J. / Seher, A. / Sebald, W. / Muller, T.D.
External linksEmbo J. / PubMed:19229295
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-3evs:
Crystal structure of the GDF-5:BMP receptor IB complex.
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsCYTOKINE/Transferase Receptor / ligand-receptor complex / cystin-knot ligand; three-finger toxn fold (receptor) / Cleavage on pair of basic residues / Cytokine / Disease mutation / Dwarfism / Glycoprotein / Growth factor / Secreted / ATP-binding / Kinase / Magnesium / Manganese / Membrane / Metal-binding / Nucleotide-binding / Receptor / Serine/threonine-protein kinase / Transferase / Transmembrane / CYTOKINE-Transferase Receptor COMPLEX

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