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TitleNeisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates.
Journal, issue, pagesNature, Vol. 458, Page 890-, Year 2009
Publish dateJan 8, 2009 (structure data deposition date)
AuthorsSchneider, M.C. / Prosser, B.E. / Caesar, J.J.E. / Kugelberg, E. / Li, S. / Zhang, Q. / Quoraishi, S. / Lovett, J.E. / Deane, J.E. / Sim, R.B. ...Schneider, M.C. / Prosser, B.E. / Caesar, J.J.E. / Kugelberg, E. / Li, S. / Zhang, Q. / Quoraishi, S. / Lovett, J.E. / Deane, J.E. / Sim, R.B. / Roversi, P. / Johnson, S. / Tang, C.M. / Lea, S.M.
External linksNature / PubMed:19225461
MethodsX-ray diffraction
Resolution2.35 Å
Structure data

PDB-2w80:
Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-2w81:
Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • neisseria meningitidis (bacteria)
KeywordsIMMUNE SYSTEM / GLYCOPROTEIN / IMMUNE EVASION / AGE-RELATED MACULAR DEGENERATION / INNATE IMMUNITY / IMMUNE RESPONSE / DISEASE MUTATION / FACTOR H / COMPLEMENT ALTERNATE PATHWAY / VACCINE CANDIDATE

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