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Structure paper

TitleStructural analysis of QdtB, an aminotransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose.
Journal, issue, pagesBiochemistry, Vol. 48, Page 1553-1561, Year 2009
Publish dateJan 8, 2009 (structure data deposition date)
AuthorsThoden, J.B. / Schaffer, C. / Messner, P. / Holden, H.M.
External linksBiochemistry / PubMed:19178182
MethodsX-ray diffraction
Resolution2.15 Å
Structure data

PDB-3frk:
X-ray structure of QdtB from T. thermosaccharolyticum in complex with a PLP:TDP-3-aminoquinovose aldimine
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-TQP:
(2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate

ChemComp-HOH:
WATER

Source
  • thermoanaerobacterium thermosaccharolyticum (bacteria)
KeywordsTRANSFERASE / aminotransferase / sugar-modification / natural porduct

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