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Structure paper

TitleStructural insights into TDP-43 in nucleic-acid binding and domain interactions
Journal, issue, pagesNucleic Acids Res., Vol. 37, Page 1799-1808, Year 2009
Publish dateMay 9, 2008 (structure data deposition date)
AuthorsKuo, P.H. / Doudeva, L.G. / Wang, Y.T. / Shen, C.K. / Yuan, H.S.
External linksNucleic Acids Res. / PubMed:19174564
MethodsX-ray diffraction
Resolution1.65 Å
Structure data

PDB-3d2w:
Crystal structure of mouse TDP-43 RRM2 domain in complex with DNA
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsDNA/RNA BINDING PROTEIN / DP-43 proteinopathy / TDP-43 inclusions / RNA recognition motif / FTLD-U / ALS / RRM / DNA-RNA BINDING PROTEIN COMPLEX

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