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TitleExtending Thymidine Kinase Activity to the Catalytic Repertoire of Human Deoxycytidine Kinase.
Journal, issue, pagesBiochemistry, Vol. 48, Page 1256-1263, Year 2009
Publish dateJun 3, 2009 (structure data deposition date)
AuthorsHazra, S. / Sabini, E. / Ort, S. / Konrad, M. / Lavie, A.
External linksBiochemistry / PubMed:19159229
MethodsX-ray diffraction
Resolution2.31 Å
Structure data

PDB-3hp1:
Crystal structure of human dCK R104M/D133A in complex with L-dT and ADP
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-LLT:
L-deoxythymidine / antivirus*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / dCK / L-dT / DM-dCK / dCK Structure Function Studies / Nucleoside Kinase / Protein-NA complex / dCK drug designing / ATP-binding / Kinase / Nucleotide-binding / Nucleus / Phosphoprotein

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