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TitleIdentification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo.
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 7673-7680, Year 2009
Publish dateDec 22, 2008 (structure data deposition date)
AuthorsMotani, A. / Wang, Z. / Conn, M. / Siegler, K. / Zhang, Y. / Liu, Q. / Johnstone, S. / Xu, H. / Thibault, S. / Wang, Y. ...Motani, A. / Wang, Z. / Conn, M. / Siegler, K. / Zhang, Y. / Liu, Q. / Johnstone, S. / Xu, H. / Thibault, S. / Wang, Y. / Fan, P. / Connors, R. / Le, H. / Xu, G. / Walker, N. / Shan, B. / Coward, P.
External linksJ. Biol. Chem. / PubMed:19147488
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-3fmz:
Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with non-retinoid ligand
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-2T1:
2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / retinol binding / Disease mutation / Retinol-binding / Secreted / Sensory transduction / Transport / Vision / Vitamin A

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