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Structure paper

TitleCrystal structures of the Apo and Holo form of rat catechol-O-methyltransferase
Journal, issue, pagesJ. Struct. Biol., Vol. 165, Page 133-139, Year 2009
Publish dateApr 4, 2008 (structure data deposition date)
AuthorsTsuji, E. / Okazaki, K. / Isaji, M. / Takeda, K.
External linksJ. Struct. Biol. / PubMed:19111934
MethodsX-ray diffraction
Resolution2.2 - 2.6 Å
Structure data

PDB-2zlb:
Crystal structure of APO form of rat catechol-O-methyltransferase
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2zth:
Crystal structure of holo form of rat catechol-o-methyltransferase
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-SAM:
S-ADENOSYLMETHIONINE

Source
  • rattus norvegicus (Norway rat)
KeywordsTRANSFERASE / METHYLTRANSFERASE / NEUROTRANSMITTER DEGRADATION / Alternative initiation / Catecholamine metabolism / Cytoplasm / Magnesium / Membrane / Metal-binding / Phosphoprotein / S-adenosyl-L-methionine / Signal-anchor / Transmembrane / TRANSFERASE (METHYLTRANSFERASE) / S-Adenosylmethionine dependent methyltransferase / Cell membrane

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