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TitleStructure-Function Relationship of Tumor Necrosis Factor (TNF) and Its Receptor Interaction Based on 3D Structural Analysis of a Fully Active TNFR1-Selective TNF Mutant
Journal, issue, pagesJ. Mol. Biol., Vol. 385, Page 1221-1229, Year 2009
Publish dateMar 5, 2008 (structure data deposition date)
AuthorsMukai, Y. / Shibata, H. / Nakamura, T. / Yoshioka, Y. / Abe, Y. / Nomura, T. / Taniai, M. / Ohta, T. / Ikemizu, S. / Nakagawa, S. ...Mukai, Y. / Shibata, H. / Nakamura, T. / Yoshioka, Y. / Abe, Y. / Nomura, T. / Taniai, M. / Ohta, T. / Ikemizu, S. / Nakagawa, S. / Tsunoda, S. / Kamada, H. / Yamagata, Y. / Tsutsumi, Y.
External linksJ. Mol. Biol. / PubMed:19084540
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-2zjc:
TNFR1 selectve TNF mutant; R1-6
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOKINE / phage display system / TNFR1 selectivity / TNF / agonist / mutant / Lipoprotein / Membrane / Myristate / Phosphoprotein / Secreted / Signal-anchor / Transmembrane

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