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TitleAn antibody loop replacement design feasibility study and a loop-swapped dimer structure.
Journal, issue, pagesProtein Eng. Des. Sel., Vol. 22, Page 93-101, Year 2009
Publish dateSep 29, 2008 (structure data deposition date)
AuthorsClark, L.A. / Boriack-Sjodin, P.A. / Day, E. / Eldredge, J. / Fitch, C. / Jarpe, M. / Miller, S. / Li, Y. / Simon, K. / van Vlijmen, H.W.
External linksProtein Eng. Des. Sel. / PubMed:19074157
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-3eot:
Crystal structure of LAC031, an engineered anti-VLA1 Fab
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / antibody / Fab / VLA-1 / domain swap / proten engineering

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