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Structure paper

TitleStructure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans.
Journal, issue, pagesJ. Mol. Biol., Vol. 385, Page 1207-1220, Year 2009
Publish dateNov 13, 2008 (structure data deposition date)
AuthorsSchlicker, C. / Hall, R.A. / Vullo, D. / Middelhaufe, S. / Gertz, M. / Supuran, C.T. / Muhlschlegel, F.A. / Steegborn, C.
External linksJ. Mol. Biol. / PubMed:19071134
MethodsX-ray diffraction
Resolution1.34 - 2.05 Å
Structure data

PDB-2w3n:
Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-2w3q:
Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans
Method: X-RAY DIFFRACTION / Resolution: 1.34 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

Source
  • cryptococcus neoformans (fungus)
KeywordsLYASE / BETA-CLASS CARBONIC ANHYDRASE / INHIBITION / SULFONAMIDE / CRYPTOCOCCUS NEOFORMANS

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