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TitleCrystal structures of rat catechol-O-methyltransferase complexed with coumarine-based inhibitor
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 378, Page 494-497, Year 2009
Publish dateNov 7, 2008 (structure data deposition date)
AuthorsTsuji, E. / Okazaki, K. / Takeda, K.
External linksBiochem. Biophys. Res. Commun. / PubMed:19056347
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-2zvj:
Crystal structures of rat Catechol-O-Methyltransferase complexed with coumarine-based inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-KOM:
7,8-dihydroxy-4-phenyl-2H-chromen-2-one

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsTRANSFERASE / Methyltransferase / Neurotransmitter degradation / Alternative initiation / Catecholamine metabolism / Cell membrane / Cytoplasm / Magnesium / Membrane / Metal-binding / Phosphoprotein / S-adenosyl-L-methionine / Signal-anchor / Transmembrane

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