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TitleConcerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.
Journal, issue, pagesNature, Vol. 456, Page 404-408, Year 2008
Publish dateJun 11, 2008 (structure data deposition date)
AuthorsMoldoveanu, T. / Gehring, K. / Green, D.R.
External linksNature / PubMed:19020622
MethodsX-ray diffraction
Resolution2.95 Å
Structure data

PDB-3df0:
Calcium-dependent complex between m-calpain and calpastatin
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-CA:
Unknown entry

Source
  • rattus norvegicus (Norway rat)
KeywordsHYDROLASE / protease core domain / penta EF-hand domains / C2-like domain / inhibitor loop-out / Membrane / Protease / Thiol protease / Phosphoprotein / Protease inhibitor / Thiol protease inhibitor

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