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Structure paper

TitleCrystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 105, Page 16888-, Year 2008
Publish dateApr 21, 2008 (structure data deposition date)
AuthorsMarcaida, M.J. / Prieto, J. / Redondo, P. / Nadra, A.D. / Alibes, A. / Serrano, L. / Grizot, S. / Duchateau, P. / Paques, F. / Blanco, F.J. / Montoya, G.
External linksProc. Natl. Acad. Sci. USA / PubMed:18974222
MethodsX-ray diffraction
Resolution2.05 - 2.1 Å
Structure data

PDB-2vs7:
The crystal structure of I-DmoI in complex with DNA and Ca
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-2vs8:
The crystal structure of I-DmoI in complex with DNA and Mn
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-MN:
Unknown entry

Source
  • desulfurococcus mobilis (archaea)
KeywordsDNA BINDING PROTEIN / PROTEIN/NUCLEIC ACID CRYSTALLOGRAPHY / ENDONUCLEASE / MEGANUCLEASE / INTRON HOMING / GENOME ENGINEERING / DNA-BINDING PROTEIN / NUCLEASE / HYDROLASE / MAGNESIUM / GENE THERAPY / GENETIC ENGINEERING / HOMING ENDONUCLEASE / PROTEIN/DNA CRYSTALLOGRAPHY

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