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Structure paper

TitleA Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has a Very Different Conformation than SNAP-25 Substrate
Journal, issue, pagesStructure, Vol. 16, Page 1588-1597, Year 2008
Publish dateJul 11, 2008 (structure data deposition date)
AuthorsZuniga, J.E. / Schmidt, J.J. / Fenn, T. / Burnett, J.C. / Arac, D. / Gussio, R. / Stafford, R.G. / Badie, S.S. / Bavari, S. / Brunger, A.T.
External linksStructure / PubMed:18940613
MethodsX-ray diffraction
Resolution1.758 - 1.9 Å
Structure data

PDB-3ds9:
A potent peptidomimetic inhibitor of botulinum neurotoxin serotype A has a very different conformation than SNAP-25 substrate
Method: X-RAY DIFFRACTION / Resolution: 1.758 Å

PDB-3dse:
A potent peptidomimetic inhibitor of botulinum neurotoxin serotype A has a very different conformation than SNAP-25 substrate
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-NI:
NICKEL (II) ION

ChemComp-HOH:
WATER

Source
  • clostridium botulinum (bacteria)
KeywordsHydrolase / Toxin / SNARE / botulism / inhibition / metalloprotease / neurotransmission / neuromuscular junction / Membrane / Metal-binding / Neurotoxin / Pharmaceutical / Protease / Secreted / Transmembrane / Zinc

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