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TitleSolution structure of a 2:1 C2-(2-naphthyl) pyrrolo[2,1-c][1,4]benzodiazepine DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.
Journal, issue, pagesBiochemistry, Vol. 47, Page 11818-11829, Year 2008
Publish dateJun 13, 2008 (structure data deposition date)
AuthorsAntonow, D. / Barata, T. / Jenkins, T.C. / Parkinson, G.N. / Howard, P.W. / Thurston, D.E. / Zloh, M.
External linksBiochemistry / PubMed:18925745
MethodsNMR (solution)
Structure data

PDB-2k4l:
Solution structure of a 2:1C2-(2-naphthyl)pyrrolo[2,1-c][1,4]benzodiazepine (PBD) DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.
Method: SOLUTION NMR

Chemicals

ChemComp-PZD:
(11aS)-7,8-dimethoxy-2-naphthalen-2-yl-1,10,11,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one

KeywordsDNA / pyrrolo[2 / 1-c][1 / 4]benzodiazepine / PBD / DNA Adduct

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