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Structure paper

TitleStructure of human prostasin, a target for the regulation of hypertension.
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 34864-34872, Year 2008
Publish dateJun 12, 2008 (structure data deposition date)
AuthorsRickert, K.W. / Kelley, P. / Byrne, N.J. / Diehl, R.E. / Hall, D.L. / Montalvo, A.M. / Reid, J.C. / Shipman, J.M. / Thomas, B.W. / Munshi, S.K. ...Rickert, K.W. / Kelley, P. / Byrne, N.J. / Diehl, R.E. / Hall, D.L. / Montalvo, A.M. / Reid, J.C. / Shipman, J.M. / Thomas, B.W. / Munshi, S.K. / Darke, P.L. / Su, H.P.
External linksJ. Biol. Chem. / PubMed:18922802
MethodsX-ray diffraction
Resolution1.45 - 2 Å
Structure data

PDB-3dfj:
Crystal structure of human Prostasin
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

PDB-3dfl:
Crystal structure of human Prostasin complexed to 4-guanidinobenzoic acid
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GBS:
4-carbamimidamidobenzoic acid / anticancer, anticoagulant, antivirus, protease inhibitor*YM

Source
  • homo sapiens (human)
KeywordsHYDROLASE / prostasin / serine protease / Glycoprotein / Membrane / Secreted / Transmembrane / Zymogen

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