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TitleCrystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alanines
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 105, Page 15334-15339, Year 2008
Publish dateMar 11, 2008 (structure data deposition date)
AuthorsIslam, M.M. / Sohya, S. / Noguchi, K. / Yohda, M. / Kuroda, Y.
External linksProc. Natl. Acad. Sci. Usa / PubMed:18829434
MethodsX-ray diffraction
Resolution1.09 - 1.4 Å
Structure data

PDB-2zjx:
Bovine pancreatic trypsin inhibitor (BPTI) containing only the [5,55] disulfide bond
Method: X-RAY DIFFRACTION / Resolution: 1.09 Å

PDB-3ci7:
Crystal structure of a simplified BPTI containing 20 alanines
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
KeywordsHYDROLASE INHIBITOR / sequence simplification / Disulfide bond / Pharmaceutical / Protease inhibitor / Secreted / Serine protease inhibitor / bovine pancreatic trypsin inhibitor

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