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Structure paper

TitleCrystal structure of the Bruton's tyrosine kinase PH domain with phosphatidylinositol
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 377, Page 23-28, Year 2008
Publish dateMay 7, 2007 (structure data deposition date)
AuthorsMurayama, K. / Kato-Murayama, M. / Mishima, C. / Akasaka, R. / Shirouzu, M. / Fukui, Y. / Yokoyama, S.
External linksBiochem. Biophys. Res. Commun. / PubMed:18809383
MethodsX-ray diffraction
Resolution2.58 Å
Structure data

PDB-2z0p:
Crystal structure of PH domain of Bruton's tyrosine kinase
Method: X-RAY DIFFRACTION / Resolution: 2.58 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-4PT:
(2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / PH domain / PIP3C4 / ATP-binding / Disease mutation / Kinase / Membrane / Metal-binding / Nucleotide-binding / Nucleus / Phosphorylation / SH2 domain / SH3 domain / Transferase / Tyrosine-protein kinase / Zinc-finger / Structural Genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI

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